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TL-988 Series
Real-time
Quantitative PCR Systems
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Real-time
Quantitative PCR Fluorescence Detecting System
The TL988 System provides an
efficiency and high-speed solution for PCR analysis. It delivers
increased sensitivity and a wider dynamic range more rapidly than
traditional PCR. QPCR gives you a choice of quantitative methods
for gene expression. The TL988 is very useful and important for life
science research and curative evaluation, and it is innovative and
pioneering products for the prevention, diagnosis, evaluation and
monitoring of diseases.
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Applications
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Quantitative PCR detection in
science research.
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Real-time quantitative PCR
detection for clinical diagnoses, such as the infectious disease,
tumor, genetic disease.
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Quantitative DNA/RNA detection of
virus, such as HBV, venereal disease, etc.
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Features
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Working
principle

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Heating &
cooling unit
Applying the advantages of
thermoelectric (TE, Peltier Effect) module makes temperature change
rapidly and uniform. The temperature ramp rate is 3.0 ¡æ/sec. This
ramping speed will allow you to complete a standard 40 cycles,
two-step QPCR reaction in about 45 minutes to 70 minutes (based on
reagents). Hot-lid design permits oil-free operation.
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Optical unit
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An array of LED collimates to
corresponding wells. High-light and long-lived LED excitation light
source does not need maintenance or preheating.
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The sensitive photomultiplier tube
PMT offers high sensitivity, broad dynamic range and low crosstalk.
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An array of detecting coaxial
optical fibers focus on each well¡¯s bottom ensure minimal light
loss.
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Special monochromator filter
reduces crosstalk and light scattering.
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The wavelength of fluorescence
detection can be changed in term of customer¡¯s requirement.
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Operation
system and Application software
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Computer¡¯s operating system
environment is MS Window 2000/XP. Application software interface is
friendly windows style, menu option, easily operating.
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Monitoring real-time amplification
plots and data analysis during a PCR run.
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Supply software package of medical
case and database management and plot display.
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Quantification
After quantitative analysis
for the standard sample, the instrument will get a standard curve of
Ct value related to copy number. Comparing the Ct value of unknown
sample with standard curve, the instrument can calculate the
original copy number of unknown sample by quantitative analysis.
TL988 has a wide linear detecting range, which can detect 101-1010
DNA copies/ml.
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Specifications
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Reagents |
FAM, FITC, SYBR,
various fluorescence PCR reagents, such as TaqMan probe, etc |
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Sample capacity |
48 well block; 96
well block; 36 well block |
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Sample handing |
Thick-walled 0.2 ml
PCR tubes |
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Sample volume |
20-100 µl |
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Wavelength of
exciting fluorescence |
470 nm |
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Wavelength of
fluorescence detection |
530 nm (changeable) |
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Monochromator device |
Filter, made in USA |
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Photo detector
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PMT (Photomultiplier
tube), made in Japan |
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Heating/cooling
devices |
TE Peltier
(Thermoelectric Peltier Effect module), made in Japan |
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Speed of ramping of
heating |
Up to 3 ¡æ/sec |
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Speed of ramping of
cooling |
Up to 2 ¡æ/sec |
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Cycling control
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Profiles |
1-9 |
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Repetitions |
1-99 |
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Steps |
1-9 |
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Set times |
1-9999 sec
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Profile linkage |
Yes |
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Thermal range |
4.0 ¡æ-99.0 ¡æ |
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Thermal accuracy |
¡À0.5 ¡æ |
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Thermal uniformity |
¡À0.5 ¡æ |
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Standard curve
efficiency |
99.7% |
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Dynamic Range |
101-1010
Copies |
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System interfaces |
RS-232C serial
interface, bi-directional |
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Computer operating
system |
Windows 2000/XP/NT |
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Input power |
AC220¡À22V£¬50¡À1Hz
; 110V(option) |
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Power |
< 800 W |
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Operating
environment |
Ambient Temperature
5¡æ-40¡æ
Relative Humidity
30%-70% |
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Weight |
15 kg |
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Size (W¡ÁD¡ÁH) |
500 mm ¡Á 400 mm ¡Á
350 mm |
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